| The asymmetric cyanine cations, thiazole orange (TO), oxazole yellow (YO), thiazole orange homodimer (TOTO) and oxazole yellow homodimer (YOYO), as well as the phenanthridine dye ethidium homodimer (EthD), bind to double stranded DNA (dsDNA). Upon complex formation with dsDNA, TO, YO, TOTO and YOYO all display a set of distinct spectroscopic alterations, the most notable of which is a very large (;Coupling of the high excitation efficiency and detection sensitivity of a laser-excited, confocal fluorescence scanning system with the large extinction coefficients (... |
