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Effects of age and tissue microenvironment on rat hepatic tumor formation and regression

Posted on:1997-10-15Degree:Ph.DType:Dissertation
University:The University of North Carolina at Chapel HillCandidate:McCullough, Karen DianeFull Text:PDF
GTID:1464390014483762Subject:Health Sciences
Abstract/Summary:
he GN6TF cell line, which is derived from chemically transformed rat liver epithelial cells, generates tumors at sc. and ip. sites of syngeneic neonatal and adult animals with exceptionally short latency. To examine the effects of the hepatic microenvironment on rat liver epithelial tumor cells, GN6TF cells were genetically modified to carry the E. coli...
Keywords/Search Tags:Rat, Cells
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