The Design And Application Research On Parallel Catalytic Reactor And Combinatorial Analysis System

With the development of chemical industry, there are increasing demands on new catalysts. However, the research and development processes of catalysts can't meet the demands of chemical industries and thus some of chemical processes were limited. Combinatorial chemistry is a high efficient methodology for discovering new catalysts and optimization of existing catalysts. The current investigation is trying to overcome the drawbacks of the traditional catalyst investigation to develop new high throughput technologies for catalyst investigation. A parallel fixed bed reactor system and a high throughput analysis instrument were designed for catalysts testing.In this investigation, a 64-channel parallel fixed bed reaction system and a diffusion-reflection imaging analysis system were designed and constructed. The parallel fixed bed reactor was composed of mass flow controllers, flow splitter, and the 64-channel reactor body, which allowed 64 catalytic reactions to be carried out simultanously.The high throughput diffusion-reflection imaging analysis system includs the colormetric diffusion-reflection imaging analysis system and the high throughput spectroscopy diffusion-reflection imaging analysis system. The imaging analysis systems could complete the spectroscopy analysis and quantification of components respectively. Combining the parallel reactor system with the diffusion-reflection imaging analysis system, a powerful methodology was formed for catalyst investigation. The developed technologies were tested in catalyst investigation for propylene selective oxidation to prepare acrolein.In the investigation, a gas flow splitter was designed to split one stream of gas to 64 equal streams of gas with a relative error within±2.0%. The flow of each channel could vary from 0²00.0mL/min. The working pressure of the flow splitter was 0.1¹.5 MPa. The splitter with good sealing was achieved in the design. There was no leaking found in working. The successful design of the splitter makes it possible to control multi flows accurately in multi-channel reactor and the data was made more comparable. For the current design, the flow of each channel in the splitter is independently adjustable, if needed. The flexible flow splitting and controlling of the splitter makes it widely applicable in other areas for flow control besides catalytic reactors.Based on the flow splitter design, a parallel fixed bed reactor with 64 channels was designed and constructed. The reactor had a uniform temperature controlling in the reactor body. In the case of heating the reactor body to 370?, a relative temperature error within 2?in reactor body was achieved.In order to do parallel product analysis, a high throughput colormetric diffusion-reflection imaging system was designed and constructed. The analysis instrument could be used to analyze compounds accurately and rapidly. Besides using in catalysis, the high throughput colormetric diffusion-reflection imaging system could also find wide applications in analyzing organic compounds and inorganic compounds.Based on the design of high throughput colormetric diffusion-reflection imaging system, a high throughput diffusion-reflection imaging spectroscopy system was also designed and constructed, which uses a monochromic light source. The system was operated by a self-designed software IPOWERSHOT to collect data and reduce data. Visible light spectra of compounds could be recorded from the instrument. The high throughput diffusion-reflection imaging spectroscopy system could analyze more quickly than commercial UV-vis spectroscopy meter. The spectra recorded by our instrument were comparable with that from the commercial UV-vis spectroscopy meter.The above designed high throughput parallel fixed bed reactor and the high throughput diffusion-reflection imaging system were used to evaluate catalysts for propylene oxidation to prepare acrolein. The purpose of the work was to test the validity in catalyst investigation. The verification experiments proved that the reactor system and the designed high throughput diffusion-reflection imaging system could give meaningful results. After testing large number of catalysts, it was found that 4.0wt%NiO/Mo_1.0-V_0.25-Te_0.11-Nb_0.12-O_x doped by 1.0wt%CuO catalyst gave the highest acrolein yield in propylene oxidation reaction. The results obtained from high throughput experiments were compared with that from the traditional fixed bed microreactor. It was found that there was no apparent difference. These investigations proved that the reactors and analysis instrument could give correct information in catalysts testing.