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Analysis Of Causes Of Splanchnic Artery Aneurysm

Posted on:2022-04-25Degree:DoctorType:Dissertation
Country:ChinaCandidate:M Y ChenFull Text:PDF
GTID:1484306350996519Subject:Clinical Medicine
Abstract/Summary:PDF Full Text Request
BackgroundAlthough the incidence of visceral artery aneurysms is low,the probability of rupture is very high and difficult to predict.Therefore,the study of visceral artery aneurysms has clinical value.The clinical application of hemodynamics is mainly concentrated in the large arteries.In the study of small and medium arteries,the research on intracranial and internal carotid artery aneurysms is one of the current hot spots,from the generation,growth,rupture of aneurysms to the choice of treatment methods.The discussion has been very mature,but the application of hemodynamics in visceral arteries is rare.ObjectiveWe hope to analyze the imaging data of real patients and compare the mechanical indicators of the aneurysm area and the non-aneurysm area to explore the hydrodynamic parameters that affect the cause of the visceral artery aneurysm.On this basis,use the ideal model to explore the influence of the stenosis of the superior mesenteric artery or celiac artery on the flow field of the pancreaticoduodenal artery.To confirm the reliability of the parameters affecting the formation of visceral artery aneurysm.MethodsThe image data of the enrolled patient is transformed into the patient's individual blood vessel model through simulation,Geomagic and SolidWorks and other software.The arteries in the original model are removed by law.The blood vessels are divided into the aneurysm area and the adjacent area through the SolidWorks software,and then the FLEUNT software is used to flow the model after the aneurysm is removed.Field analysis.The post-processing software Tecplot was used to collect the hydrodynamic parameters of the two regions for comparison.The effect of stenosis on the hydrodynamic parameters of the collateral artery wall.ResultsExcessive or low shear stress on the wall of the visceral artery may lead to the formation of aneurysms.The normal range of the time average wall shear stress is between 0.5N/m2 and 1.7N/m2.The normal range of the maximum of the wall shear stress is from 2.5N/m2 to 7.9N/m2.Excessive wall shear stress gradient may also be one of the reasons for the formation of aneurysms.The results of the ideal model show that when the diameter of the artery exceeds 70%,the collateral circulation vessel wall shear stress and other indicators exceed the normal range,which may lead to the formation of collateral vessel aneurysms.The arteries are high.Considering it is a high incidence area of visceral aneurysms,it should be taken seriously in clinical work.ConclusionsThis study preliminarily delineates the normal range of wall shear stress,but it still needs further study and accuracy.When the diameter of internal visceral arteries exceeds 70%,fluid mechanics is required to provide a large number of new clinical indicators for the study of vascular surgical diseases,and provide new research directions for the analysis of the causes of visceral aneurysms.
Keywords/Search Tags:Hemodynamics, visceral artery aneurysm, wall shear stress, wall shear stress gradient
PDF Full Text Request
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