Research On The Pharmacokinetices Of The Rare Earths In Mice

This experiment was designed to study the effects of RE on the feed intake, digestion, feather and spirit of the mice , to research the dynamic rules of the RE' s assimilation, distribution, elimination , and to study the security of RE , so as to offer some theoretical basis for livestock and poultry.128 forty-day-old male mice, divided into eight groups with four replicates per group, were fed RE nitrate diet with the dosage of 0, 50, 100, 200, 400, 600, 800, 1600mg/kg. It was revealed that the apparent assimilated amount was the lowest in the 50mg/kg group, which was only 6. 4328u? Diversely, the amount was the highest in the 400mg/kg group, having the significant difference with others (P<0.01) .The apparent digestable rate was higher in the 50 mg/kg and 100 mg/kg groups, respectively 1.81% and 1.91%. The lowest one was in the 1600mg/kg group, only 0.16%. At the same time .there was significant difference in each group (P<0.01). The feed intake had no significant difference (P>0. 05) in the first five groups, however the latter three groups had significant difference with the former five groups (0. 01