The Localization And Expression Of Prolactin Receptor MRNA At Follicles Of Inner Mongolia Alpas Cashmere Goat

The localization and expression of prolactin receptor from Inner Mongolia Alpas cashmere goat were studied by Sacpic Staining,in situ hybridization and western blotting.Samples of skin were taken at interval three months from birth, three months old, six months old, nine months old, ten months old or twelve months old, which correspond to summer, autumn, winter and spring. Paraffin sections of hair follicles were stained with Sacpic staining and in situ hybridization.The protein of prolatin receptor is abstracted from samples of skin in order to study on expression of prolactin receptor.There are prolactin receptors in outer root sheath,dermal papilla and inner root sheath. The growth of primary follicle is continuous. The growth of the second follicle is vary by season.In autumn and winter,the speed of the growth of the second follicle is quick.In summer,that of the growth of the second follicle is slow.lt is same as the growth of cashmere.The weight of prolactin receptor is 87kD and 71 kD .The qualitity of prolactin receptor.is vary by season. According to.three results from above,we can conclude that prolactin is relevant to the. hair growth cycle of the Alpas cashmere goat.