Study On Chemical Constituents Of The Algae Hydroclathrus Tenuis And The Marine Sponge Phakellia Fusca

The chemical constituents of the algae Hydroclathrus tenuis and the sponge Phakellia fusca collected from the South China Sea were studied in the paper. Sixteen compounds have been isolated and identified from the algae Hydroclathrus tenuis. The stereo structure of compound 1 was established by X-ray diffraction analysis. Compounds 1 and 10 were isolated from natural resources for the first time. All the Compounds were isolated from this algae for the first time. Four compounds were isolated and identified from the sponge Phakellia fusca.Ten pure compounds isolated from the algae Hydroclathrus tenuis were identified as 1,4-bis(benzyloxy)benzene(1), (2S,3R,4R)-1,2,3,4,4a,5,6,6a,7,8,8a,9,10,11, 12,12a, 14,14a, 14b-icosahydro-2,3-dihydroxy-8a-(hydroxymethyl)-4,6a,6b, 11,11,14b-hexamethylpicene-4 -carbldehyde(2), (3S,6R)-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-10,13-dime thyl-17-((R)-6-methylheptan-2-yl)-1H-cyclopenta[a]phenanthrene(3), ethyl palmitate(4), N-(1-hydroxyctadecan-2-yl)nonadecanmide(5), 2,3-dihydroxy-N-(1,3-dihydroxyoctadecan-2-yl)tetracosanamide (6), octanoic acid(7), (25R)-5α-spirostane(8), 2-hydroxy-N-(1,3,4— trihydr- oxytetracosan-2-yl)docosanmide (9), (1-β-D-gucopyranosy-(2S,3R) -2-N-[2R-hy-droxy-octadecyl]-octadecasphinga(10) by UV, IR, ¹HNMR, ¹³CNMR, ¹H-¹HCOSY, HMQC, HMBC, EIMS, HRMS。Four compouds isolated from the sponge Phakellia fusca were identified as 5,6,7, 8-tetrahydro-8-(2-hydroxypyridin-3-yl)-[l,2,3]triazolo[4,5]azepin-4(3H)-one(12),N-(l,3-dih ydroxytriacontan-2-yl)-2' -hydroxydodecanmide-1"-O-α-D-glucopyranosyl-(6'' →1''')-α-D- glucopyranoside (13), (3S)-2,3,6,7,8,9,10,11,12,13, 14,15 ,16,17-tetradecahydro-10,13-di methyl-17-((R)-6-methylheptan-2-yl)-1H-cyclopenta[a]phenanthren-3-ol(14), fusca alkloaid(15) by UV, IR, ¹HNMR, ¹³CNMR, ¹H-¹HCOSY, HMQC, HMBC, EIMS, HRMS。...