The Research Of Synthesis Of The New Type Of Pyrrole Pesticide Chlorfenapyr

The chlorfenapyr is part of one kind of arylpyrrole pesticide acariasis and has'primarily pesticide properties.In this paper,the study of preparation for chlorfenapyr and its intermidates is emphaticallydiscussed.The intermidates of p-chlorophenylglycine, 4-(p-chlorophenyl) 2-trifluoromethyl-3-oxazolin-5-one,2-(p-chlorophenyl)-5-(trifluoromethyl)pyrrole3-carb onitrile, 4-bromo-2-(p-chlorophenyl)- 5-(trifluoromethyl)pyrrole-3-carbonitrile and chlorfenapyr are synthesized and their compounds'structure are characterized.In this paper,Several methods are elaborated for the synthesis of chlorfenapyr, corresponding methods are emphatically discussed . Corresponding methods are.begined with p-chlorophenylglycine,proceeding from Bucherer-Bergs reaction bromate reaction and obtaining better ways to stnthesize chlorfenapyr at last.According to these results, with corresponding methods, by-product happening during preparing p-chlorophenylglycine was inquired and producing p-chlorophenylglycine with coherent methods was discussed and 6btaining better process to prevent red oily compound from happening.. This has given a strating point for industrial applying. The separate or not is not effect the yield of p-chlorophenylgly cine. Preparing 4-(p-chlorophenyl)-2-trifluoromethyl-3-oxazolin-5-one can simply disposed and be directly used the next reaction.This provide the reliable data for the industry.