The Study Of Electrochemical Characteristics And Analytical Application Of Calix[n] Arene Film Modified Electrodes

It is well known that calixarenes are a group of cavity-shaped cyclic molecules comprising phenol units linked via alkylidene group. They possess special cavity structure and thus are able to form host-guest inclusion complexes with a variety of molecules selectively. If calixarenes were modified on electrode surface to form chemically membrane-modified electrodes, some molecules with electrochemical characters resemble or peak potential similitude may be separated each other. In this paper, the voltammetry behaviors of the electrochemical characters of p-tert-butyl- calix [8] arene film modified glassy carbon electrode (GCE) and suffocate calix [6] arene in the solutions have been studied respectively. Furthermore, a very good peak potential separation of three kinds neurotransmitters at p-tert-butyl-calix [8] arene film modified electrode had been also gained. The main results are expressed as fellows:1: The voltammetry behavior of p-tert-butyl- calix [8] arene film modified glassy carbon electrode (GCE) has been studied. In the ammonia solution + ammoniate chloride buffer solution (pHS.O), an obvious reduction peak controlled by diffusing is observed and the electrode reaction process has been studied particularly. Moreover, the kinetic parameters have been obtained too.2: A method for separation of dopamine, 5-hydroxytryptamine and adrenalin; by p-tert-butyl-cah'x[8] arene chemically modified glassy carbon electrode with differential pulse voltammetry is described. The result shows a good peak potential separation for these three kinds of neurotransmitters. The peak currents are in linear relationship to the concentrations of dopamine, adrenalin and 5-hydroxytryptamine in the ranges of 2.0 X 10-6mol/L ~ 1.1 X 10-3mol/L, 2.0 10-6mol/L ~ 2.8 X 10-4mol/L and 9.0 X 10-6mol/L ~ 1.4 X 10-3mol/L respectively. This is the first time to determine three neurotransmitters at same time by electrochemical method and the kinetic parameters have been obtained too.3: In this paper, the voltammetry behavior of sulfa-calix [6] arene has been performed for the first time by using many electrochemistry methods at glassy carbon electrode. In the potassium dehydrogenate phosphate + sodium hydrogen phosphate buffer solution (pH5.2), sulfa-calix [6] arene has an obvious reduction peak controlled by diffusing. The reduction peak currents are a fine linear relationship with sulfa-calix [6] arene concentrations in the range of 6.0x10-6 ~1.0 10-3mol/L with detection limit of 5.0x10-6mol/L. Based on the method, the quantitative analysis sulfa-calix [6] arene is primarily established by electrochemistry. In addition, the electrode reaction process has been studied particularly and the kinetic parameters have been obtained also.