The Study Of 2-Heptanone Preparation

This article studies the preparation of greenness environment solvent, 2-heptanone, with DMK(propanone) and BD(n-butyl aldehyde), via cross aldol condensation, dehydration with acid and catalyzed hydrogenation. Especially it introduces the parameter of the cross aldol condensation and side-reaction controlling, the midterm products separation, and catalyzed hydrogenation.Hydroxide ketone was prepared with DMK and BD catalyzed by the liquid base(NaOH solution) first, especially studied the affect of all the factors to cross aldol condensation, including the amount of catalysts, reaction temperature, feed and reaction time, stuff ratio and co-catalysts etc.. And the condensation conditions were also optimized. The excellent results were achieved under the following conditions: 15% NaOH solution 30 mL, 15 C reaction temperature, 1.5 h feed time, the stuff quota is 1:3. And adaptive co-catalyst ZnCl2 can improve the yield remarkably.The preparation of hydroxide ketone with solid base OH-1/CaO and OH-1/MgO was studied. It was proved that the OH-1/MgO has the better selectivity. And the solid base calcined has the superior catalyst performance.The preparation of alkene ketone from hydroxide ketone dehydrogenation was studied, H3PO4 was selected as the super catalyst.The preparation of MAK hydrogenated from alkene ketone with Pd/C and Raney Ni was especially studied. The dose, pressure, temperature and other factors on hydrogenation were studied. The results showed that Pd/C was super to Raney Ni with better hydrogenation capability.The ultimate product was proved to be 2-heptanone by IR, GC, MS and GC associate with MS.The side-reactions were studied primarily in this paper, and the process of cross-aldol condensation were analyzed initially in kinetics.