Determination Of L-Arginine And VitaminK₃ By Copper(Ⅱ)-Catalysed Oscillating Chemical Reaction

Kinetic methods of analysis are currently regarded as highly effective tools in chemistry. These non-linear phenomena, known as oscillating chemical reactions have aroused increasing attention in recent years in order to characterize non-linear chemical phenomena in the context of theoretical and experimental chemical kinetics. This work develops new methods using copper( II )-catalyzed oscillating chemical reaction for quantitative analytical determinations of VitaminK3, and L-Arginine , the accuracy and selectivity of these methods are well-pleasing. The main content consists of three parts.Kinetic methods of analysis are currently regarded as highly effective tools in chemistry. These non-linear phenomena, known as oscillating chemical reactions have aroused increasing attention in recent years in order to characterize non-linear chemical phenomena in the context of theoretical and experimental chemical kinetics. This work develops new methods using copper( Ⅱ )-catalyzed oscillating chemical reaction for quantitative analytical determinations of VitaminK3, and L-Arginine , the accuracy and selectivity of these methods are well-pleasing. The main content consists of three parts.Part Ⅰ The Oscillating Chemical Reaction and Its ApplicationThe definition of oscillating chemical reaction and its principle were introduced. The development of study on oscillating chemical reaction applied to analytical chemistry, studying in life science, and so on was also summarized.Part Ⅱ The Effect of Vitamin K3 on Cu( Ⅱ )-H2O2-NaSCN Oscillating Chemical ReactionThe effect of VitaminK3 on the copper( Ⅱ )-catalyzed oscillating chemical reaction between hydrogen peroxide and sodium thiocyanate was studied. The reaction is implemented in a steady closed system. The change of the oscillation period are linearly proportional to the VitaminK3 concentration both from 5.26× 10-7 to 2.17×10-4 mol L-1 and from 3.21×10-4 to 8.87×10-3 mol L-1, respectively. The related coefficients are 0.9981 and 0.9975. Some aspects of the interaction of VitaminK3 with the oscillating chemical system are discussed. Part Ⅲ Determination of L-Arginine by an Oscillating Chemical ReactionA new analytical method for the determination of L-Arginine by its perturbation by different amounts of L-Arginine on the copper( Ⅱ )-catalysed oscillating reaction between hydrogen peroxide and sodium thiocyanate in an alkaline medium is proposed. The reaction is implemented in a closed system. The system perturbation results in changes in the oscillating amplitude and period, which are proportional to the L-Arginine concentration. Three different methodologies were used to address the determination. The dynamic range lies between 1.48×l0-5~3.85×10-4 mol L-1and 2.5×10-6~3.38×10-4mol L-1, respectively. The method features good precision (RSD<0.85%) due to the fact that the closed system has a noticeable stabilization. Some aspects of the interaction of L-Arginine with the oscillating chemical system are discussed.