Preparation Of Polystyrene Supported Hypervalent Iodine Reagents And Their Applications

In this dissertation, the preparation of the polystyrene supported versatile hypervalent iodine reagents and their application in organic synthesis were investigated. Firstly, we prepared poly[4-diacetoxyiodo]styrene and poly{[4-hydroxy(tosyloxy)iodo]-styrene}. Secondly, we made our endeavor to extend the range of useful application of them in organic synthesis: 1) poly [4-diacetoxyiodo] styrene was used as an efficient reagent of synthesis 3,5-disubstituted-thiazolo[2,3-c]-s- triazoles and it was also applied to the synthesis of phenylacetaldehyde from styrene and so on. 2) poly{[4-hydroxy-(tosyloxy)iodo]styrene} was an effective Hofmann rearrangemental reagent, and has been successfully employed in the synthesis of alkylammonium tosylates from a series of primary amides. The conditions were generally mild and yields from good to excellent, surpassing those traditionally obtained.At last, we explored the recollect and reuse of polymer-supported iodine reagents and got good results.