Synthesis And Property Study Of The Poly (Amidoamine) Dendrimers

Dendrimers are a new category of dendritic macromolecules appearing during the mid of 1980s, which are three-dimensional, highly ordered and can be controled from a size on the nanometer scale and design molecule size, shape, structure and functional groups. Their extraordinary three-dimensional structure and unique single-dispersity make the macromolecules bearing unique qualities and functions. The unique structure suggests a broad range of applications such as (guest/host) chemistry, analytical chemistry, molecular recognition, medical carrier, information saving material, nano-material, light-electron switch, LCD material, efficient catalysis, purifying polluted water, sensor and film and so on. In the last few years, the study and research on dendrimers have attracted the interest of biochemistry, catalysis, nano-material.Since the first report of organic and polymeric materials showing optical-gain and stimulated emission properties, there has been increasingly interest in exploiting these materials in laser applications. After dendrimers appeared, the macromolecules having optical property were considered connecting with dendrimers in order to research photoelectricity property of dendrimers containing azobenzene and character of dendrimers. Therefore, the aspect research enhance understand on azobenzene photoelectricity property and offered theoretical guidance to molecule design. In addition, the research of dendrimers containing benalkyne becomes active. To our best knowledge, there are few literatures which have reported the synthesis of the dendrimers containing salicylic acids and coumarin-3-acyl chloride on the Periphery.In this thesis, we firstly designed and synthesized the poly(amidoamine) dendrimers as ethylenediamine core and optimized experimental condition. Furthermore, we studied fluorescent property of different generation. Following, owning to the structure of dendrimers which have compact surface groups, kinds of dendrimers having optical property were prepared from PAMAM as raw material and researched optimal conditions to determine the fluorescence. And then, we study synthesis of the dendrimers with different core. Finally, we computed the energy of the low generational dendrimers of PAMAM PAMAM-S, PAMAM-X by Mol. Mechanics and Mol. Dynamics simulated.Series I : Firstly, it concisely summarized the development of dendrimers, its structure character, synthesis and current application research. Specially, in order to stand out our aim and significance of study, it seperately summarize the dendrimers with fluorescent property.Series II: Synthesis and property research of poly(amidoamine) dendrimers. The optimal conditions of synthesis of poly(amidoamine) dendrimers were studied on reaction temperature, reaction time and dropping the raw material and so on in chapter two. By fluorescence analysis, it is considered that the integral generational dendrimers have fluorescence. However, the half generational dendrimers do not have the property. The fluorescent intensity of the complex of the dendrimers with metal ions increases weakly when add metal ions to dendrimers. The polyamidoamine dendrimers, PAMAM-X and PAMAM-S, were synthesized respectively by decorated the PAMAM dendrimers on the periphery in chapter three and four. The fluorescent analysis indicated the PAMAM-X and PAMAM-S have strongly fluorescent emission and studied its condition. The fluorescent intensity and emission position of PAMAM-X and PAMAM-S are affected by generation, pH, concentration and solvent. The fluorescent properties of PAMAM, PAMAM-S, PAMAM-X dendrimers have been contrasted in chapter five. In chapter six, we studied synthesis of the asymmetry, two branching core. The compounds can be used synthesis in the divergent and convergent approaches.