Preparation Of Polylactide Microspheres And Ginsenoside Rg₃ Microspheres Analysis

Ginsenoside Rg3 is a drug isolated from ginseng which had beenproved to have the effect of anti-tumor . Since the ginsenoside Rg3 wasproved effective, the scientists from many countries pay much attentionon it.In China,ginsenoside Rg3 has been authorized to use in clinic asan new anti-tumor durg in 2001.Now, ginsenoside Rg3 has beenproduced in batch.Now ginsenoside Rg3 has been used in clinic asanti-tumor drug..But the character of ginsenoside Rg3 that it's easy tobe acid hydrolysis in stomach ,digestible in body and concentration indrug low significantly limited its effect.The microsphere encapsulation technology is a method that thecore material such as solid,liquid or gas etc. was encapsulated into thecoating material and formed microspheres whose diameters were from1um to 1000 um. Sustained-release,controlled-release drug system is anew drug target medication system developed from 1970s, usuallycalled sustained-microspheres.For sustained-microspheres have manyadvantages on other drug medication, it was universally researched.Through using it ,the drug can be distributed better in body and havemore target function, the aim of drug spare and effect enhance can beobtained.This research using biodegradable material poly lactide(PLA) asthe coating material, first adopt alabum and poly vinyl alcohol as...