Study On The Synthesis Of The Diazole Derivatives

In this thesis, 1-aryl-3-benzoyl-2-thioxoimidazolidin-4-one, 1-aryl-3-benzoyl-5-chloro-2-thioxoimidazolidin-4-one and 1-ary-2-thioxoimidazoli-din-4,5-dione were prepared by the reaction of 1-benzoyl-3-arylthiourea with chloroacetyl chloride, dichloroacetyl chloride, oxalyl dichloride. In addition, we studied on the reaction of α, β-unsaturated ketones with hydrazine hydrate in the presence of triphenylphosphine as catalyst. The results showed that the reduction product of carbon-carbon double bond and pyrazole derivatives were formed, which depended on the structure of α, β-unsaturated ketones. The structures of all compounds obtained were confirmed by IR, 1~H NMR,(13)~CNMR and MS spectra.