Synthesis,Characteristic And Its Release Properties In Vitro Of Thermosensitive Intelligent Materials Based On N-Isopropylacrylamide/2-Hydroxyethyl Methacrylate

Synthesis, characteristic and its release properties in vitro of thermosensitive intelligent materials based on N -isopropylacrylamide/ 2-hydroxyethyl methacrylate were studied in this paper.N-isopropylacrylamide monomer , its polymers and hydrogels , such as PNIPAAm hydrogels , NIPAAm/HEMA , NIPAAm/NVP hydrogels; were synthesized and further temperature sensitivity was studied in this paper. A novel temperature- sensitive functional biomaterial N-isopropylacrylamide -grafted-2-hydroxyethyl methacrylate polymer (NIPAAm-g-HEMA) using APS(ammoniumpersulphate)/Na₂S₂O₅(Sodium pyrosulfite) as redox initiator were prepared in an aqueous medium; A novel thermo- sensitive PNIPAAm/HEMA interpenetrating network hydrogels P (NIPAAm-I-HEMA) were prepared with both PNIPAAm and 2-hydroxyethyl methacrylate hydrogels which were synthesized by free-radical aqueous solution polymerization using APS(ammonium persulphate)/Na₂S₂O₅(Sodium pyrosulfite) as redox initiator in a Simultaneous interpenetrating network process. A novel temperature-sensitive functional biomaterial N-isopropylacrylamide...