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Synthesis Of The Chitosan Derivation And Study Of Its Antibacterial Activities On Cotton Fabrics

Posted on:2007-04-25Degree:MasterType:Thesis
Country:ChinaCandidate:J X ZhaoFull Text:PDF
GTID:2121360185962825Subject:Materials Physics and Chemistry
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Microorganism not only can change the color of textile fiber products, make them to be mildew and degenerate etc., also can stimulate skin and induce kinds of skin diseases which are harmful to the human health. Therefore, the research and exploitation of the antibacterial fabrics has the extremely vital significance to the health of human., especially in such a condition or environment that the soldiers were in the war time, the mining workers worked long time in the outside and so on.Chitosan is a kind of natural, safe, non-toxic organic high polymer which has the antibacterial activities, but it is difficult to dissolve in water when pH is over 6.5, which limits its application. In order to enhance its antibacterial function on cotton fabrics, people have done much research work about modification of chitosan, e.g. carboxy methyl chitosan(CMC) which has a good water-solubility, moreover has stronger antibacterial activities than chitosan. The inhibitory rate of CMC at 1.25 mg·mL-1 to S. aureus E. coli and C. albicans respectively is 70.6%, 47.4%, 54. 3%; the bactericidal rate at 10 mg·mL-1 to S. aureus ,E. coli respectively is 56% and 73%The non-toxic water-soluble quaternary ammonium salt of chitosan (TMCI) was obtained by the chemistry modification of chitosan,. The experimental result indicated that: after chemicals modification, the TMCI not only dissolve completely in water, which broaden its application greatly, and strengthen its antibacterial activities to the bacterium and the fungus. The MIC of TMCI to S. aureus , E. coli respectively is 1.0 mg·mL-1 ,1.25 mg·ml-1, the MBC respectively is 7.5 mg·ml-1,10 mg·ml-1; the MIC to...
Keywords/Search Tags:chitosan, the quaternary ammonium salt of chitosan, antibacterial activities, fabrics
PDF Full Text Request
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