An Improved Indium-Mediated Reductive Intramolecular Cyclization Of 2-Nitrochalcones To Quinolines

In this article, the author had tried to find out a new method that the reductive intramolecular cyclization of 2-nitrochalcones under the iodine catalysis metal indium and fourteen quinoline derivatives were obtained (4a-4n). These compounds were . characterized by ¹H-NMR, ¹³C-NMR, IR and MS. The experimental result indicated, the reductive intramolecular cyclization was rapidly occurred and 2-nitrochalcone derivatives were transformed into the corresponding quinoline derivatives in good yields. The production rate generally enhances 10-40% compared to predecessor's study.Meantime, the author described the synthesis of the novel phenylboronic acid derivatives such as 2-[4-(dihydroxyboryl)phenyl]carbamoylanthraquinone and 2-anthr aquinonyl-5-(4-dihydroxyboryl)phenyl-l,3,4-oxadiazole. Two compounds were obtained though route (1) and (2) from anthraquinone-2-carboxylic acid. Two...