Research On Bioceramic Coating On Surface Of Titanium Alloy Implant

With favorable combination property and biocompatibility, Hydroxyapatite on titanium substrate is the hotspot in the range of biomaterial research. Based on Micro-arc Oxidation technology, the coating of bioceramic that it has calcium phosphate compound was fabricated on the surface of titanium alloy substrate with the facility of Micro-arc Oxidation made by ourselves. The influence to the property of coating with different processing parameters was investigated, and its biocompatibility was preliminary studied. Experiment of the coating immersion in simulated body fluid (SBF) was processed, and sedimentation mechanism and growth process on surface of the coating were discussed.The bioceramic coating that it has calcium phosphate compound was fabricated on titanium alloy substrate through Micro-arc Oxidation technology, which the electrolyte were composed of phosphatic ammonia salt and Ca3(PO4),CaCO3,(CH3COOH)Ca?H2O individually. It was shown from experiment that the coating was the ceramic intermixture which was porous and firmly combined with the titanium substrate. The ingredient of the coating was mainly determined by the direction of the electrolyte and the calcium content of the coating was more when the (CH3COOH) Ca?H2O was elected as than others did. The other processing parameters, such as temperature of electrolyte, discharge time and current density and voltage of Micro-arc Oxidation, were also influenced the characteristic of the coating. Under processing condition at present, the optimized processing parameters were as follow: Ca/P was about 9～15,electrolyte temperature was 30～50℃,time within 80 minutes,current density was about 1.0A/cm2 and voltage was 70～150V.Biocompatibility is one of important evaluation of biomaterial. Primarily evaluation of biomaterial was carried out with acute hemolysis test and cytotoxicity experiment. The results of biocompatibility experiment showed that the coating's acute percentage of hemolysis is 2.03%, which can consider it has no hemolytic action, and the coating's cytotoxicity is the first ranking by MMT assay, which can meet the material biocompatibility demand for clinical application.Simulated body fluid (SBF) cultivation is the most elementary experiment method to measure the material's biological activity. With the help of SEM, EDS and XRD, The coating made by Micro-arc Oxidation that immersed in SBF in several...