Study On Purification Of Fish Oil And Seal Oil With Molecular Distillation

Ω3 poly unsaturated fatty acids (PUFA,EPA,DHA,DPA) was called indispensable fatty acids for people which could not be synthesized by ourselves, and it must be incepted from outside.ω3PUFA was widely contained in fish oil and seal oil. It was significant to optimize the separation technology ofω3PUFA and actualize industrialization.The differential equations of thermal transfer based on the analysis of wiped film molecular distillation mathematic model were solved by numerical method. Based on the VKL70 wiped film molecular distiller, the effects of Distillation Temperature on total contents of officinal compositions were primarily discussed by numeric simulation with fish oil and seal oil as feed liquid. The simulation result and experimental data inosculated very well. It provided the foundation for optimization of operating parameter of wiped film distiller. The distance between the evaporation surface and condensation surface of molecular distiller was far more than the molecular average free path. It could be proved to be true by the calculation of molecular free path of fatty acids in fish oil and seal oil under different temperature and pressure. The result showed that the separation effect was hardly changed. So the conclusion made it possible to apply experimental distiller to industrial plant.In this dissertation, the extraction ofω3PUFA from fish oil and seal oil with VKL70 small scale molecular distillation apparatus and VK200-40 molecular distillation pilot plant from VTA, GERMANY was studied. In distillation process, the influence of operating parameters on total contents and yield of officinal compositions was investigated, such as distillation temperature, feed rate and rotor speed. The optimum processing condition wais obtained, and it layed a foundation for the further industrial manufacture.A lot of medicinal research showed that the officinal value of esterified EPA,DHA,DPA was very different from the unesterified. Thus the unesterified fish oil and seal oil were used as material to extract the officinal compositions for the first time. The product of high quality and yield was obtained by the molecular distillation technology with unesterified fish oil and seal oil as material.