Studies On Commercial Producing Process Of Hepatitis A And Mumps Combined Vaccine, Freeze Dried

Some infectious diseases have gained effective control after the use of preventive vaccine throughout the whole world, and the incidence of disease and morality rate of some familiar infectious diseases has been reduced consumedly. With the rapid development of molecule biology and cellular biology along with some correlative subjects, some new vaccines have been studied and developed But the increase of the kinds of vaccine surely goes with a series of problems, such as the increase of childrens'vaccinal times and the difficulty of the management of vaccine. Therefore, the development of the united vaccine and united immunity has become the developmental trend of bacterain study recently. There has been a long history of the study and production of united vaccine interiorly and overseas, many products have been published and has gained broad use. Its virtues are to reduce the vaccinal times, to letdown the expense of inoculability and management, hence the object to prevent manifold diseases can be achieved. Accordingly some good social and economic benefit can be gained. Some materials indicate that the simultaneous inoculability of hetatitis vaccine and parotitis vaccine has no effect on the immunity responsion of mumps vaccine, also the immunity effect of the hepatitis vaccine. At one time after the inocyulatility some aggravation feedback and abnormity feedback haven's emerged. So we believe that the mumps vaccine and hepatitis decreasing poison alive vaccine can be simultaneously inoculated. This study fruit has become researchful basis of freeze-out hepatitis parotitis united vaccine.This article begins with the study of creative technics of united vaccine, mainly carry through the following aspects of work:(1)the optimal proportioning rate of the two unit price vaccines is 1:1;(2)NO.1 freeze-dry protective pharmaceutical has been confirmed the optimal freeze-dry protective pharmaceutical direction;(3)three groups vaccines has been produced continuously according to certain creative technics, and united vaccine of freeze-dry hepatitis and parotitis whose virus instilling degree are below the two unit price vaccine. And this proves that the creative technics flow is feasible, safe and steady, and establishes the basis of further experiment.In a word, this article has established substantial basis for the development of freeze-dry hepatitis and parotitis united vaccine and had an important practical meaning. In order to validate whether it can become ideal united vaccine, we have a lot of other work to do, including to experiment on animals to further prove whether the two viruses of the united vaccine exist across interference and aggravation feedback; whether they may effect each immunity responsion, to insure the study coincide with the basic request, to support sufficient and reliable foundation for the further study.