The Study Of The 1, 3-dipolar Cycloaddition Reactions Using Azomethine Ylides

A series of imine esters were synthesised by the addition and dehydration ofamino acid esters to aldehydes. On the basis of this, we have get the azomethineylides by using the silver nitrate as a catalyst. Then the 1, 3-dipolar cycloadditionreactions were studied using azomethine ylides as the starting marerials.The thesis mainly contains two parts. The first part is about that five-membered rings compounds were synthesised by the addition ofα,β-unsaturated ketones to imine esters using the silver nitrate as a catalyst. The second part is about that five-membered rings compounds were synthesised by the addition ofα,β-unsaturated cyanoacrylates to imine esters using the silver nitrate as a catalyst. All products are unknown compounds and their structures have been determined by IR, ¹H NMR,¹³C NMR, MS and the element analysis.The effect of solvent polarity, temperature and time on the reactions were examined and reaction scale was changed, in order to get the optimized system.The potential mechanism of the cycloaddition reactions. was studied, azomethine ylides were synthesized by the imie esters and the silver nitrate. Then the five-membered rings compounds were synthesised with unsaturated ketones/ cyanoacrylates and azomethine ylides.