Studies On Synthesis, Characterization And Supramolecular Recognition Of Novel Redox Active Thiacalix[4]arene Multisite Receptors

Thiacalixarene is greatly important to both the field of supramolecular chemistry and practical domain of advanced techniques of ion transport, molecular switch, molecular devices and chemical sensors. This dissertation is an account of the design, synthesis, characterization, and supramolecular properties of novel ferrocene-based open-chain thiacalixcrown multiple recognition sites receptors. It is divided into three sections. The first part briefly reviews recent research progress of thiacalixarene receptors, including molecular design, chemical synthesis and their application in supramolecular and coordination chemistry.The second part describes the preparation, characterization and supramolecular electrochemical recognition properties of two novel ferrocene acyl thiourea-based open-chain thiacalixcrown receptors. Their structures were characterized by elemental analyses, IR, ¹H NMR, ⁽130C NMR and MS, as well as for one compound being determined by X-ray diffraction techniques. Such receptors shown selective recognition function towards H₂PO₄^- and AcO- anions.The third part focuses on the synthesis, characterization and supramolecular recognition properties of three novel ferrocene amide-based open-chain thiacalixcrown multi-site receptors. The recognition and sensing properties of these new receptors were investigated by the cyclic voltammetry, 1H NMR titration and fluorescence titration techniques. It was found that such redox-active receptors show a high selectivity towards H₂PO₄^- and Eu³⁺ ions.