Synthesis And Property Of Theophylline Molecules Imprinted IPN

Molecularly Imprinting Technology (MIT) has received more andmore attentions because of its peculiar properties as the prearrangement,recognition, and practicability. Interpenetrating Polymer Networks (IPN)has extensive applications in the functional polymers due to itscompatibility and maintenance for the first network. If the MIT and IPNare combined, the MIT/IPN adsorbents are synthesized, their applicationsin the adsorptive separation will be very wide.This thesis is composed of three parts:In the first part, theophylline imprinted IPN composed of sulfonatedpolydivinylbenzene/polydivinylbenzene is obtained by suspensionpolymerization. The adsorption isotherms of theophylline onto theadsorbent from the aqueous solution are measured, and the adsorptionproperties of the non-imprinted adsorbent are compared. The resultsshow that the molecular structures of the imprinted and non-imprintedadsorbents are similar. However, the imprinted adsorbent displays betteradsorption property and seletivity.In the second part, another molecularly imprinted IPN,polydivinylbenzene/poly crylic acid is synthesized by using theophyllineas a template. The adsorption isotherms are measured by the staticadsorption method, and the adsorption enthalpies, adsorption freeenergies, and adsorption enthalpies are calculated. The adsorptionenthalpies are in the range of 21 kJ/mol～26kJ/mol, implying thehydrogen bonding between the adsorbents and theophylline is the maininteraction.In the third part, cholic acid imprinted IPN, polydivinylbenzene/poly triallylisocyanurate, is prepared. The adsorption properties of theadsorbent for cholic acid from ethanol solution are discussed. The results indicate that the adsorption process is controlled by the adsorptionenthalpies.