Research On The Nitrogen-containing Ferrocenyl Hetertocyclic Compounds And The Cyclization Of Amidine Compounds

Firstly in this article, two series compounds ofN-(4-Hydroxy-4-methyl-3-aryl-thiazolidin-2-yl)-ferrocenylamide andN-(4-Hydroxy-4-phenyl-3-aryl-thiazolidin-2-yl)-ferrocenylamide weresynthesized from unsymmetric ferrocenyl thiourea derivatives, which wereformed by ferrocenyl formyl-acid.Secondary, benzimidazole derivatives were prepared by the reaction ofiodobenzene diacetate with N, N'-diphenylbenzamidine at room temperature.Finally, the compounds N-acetylbenzamide (5a～5j) andN-(5-oxo-5H-1,2,4-dithiazol-3-yl)arylamide 6 were formed by the reaction ofthe IBD with benzoyl isothiocyanate.The structures of compounds were confirmed by ¹H NMR, ¹³C NMR, MS,IR data. In addition, the structure of 2b and 6b was comfirmed by RigakuMercurry CCD X-ray imaging.