Research Progress On Preparation And Biocompatibility Of Polymer/Nano-materials Composites

The particular properties of the nanomaterials have attracted comprehensive attentions. Preparing the composite materials which have outstanding performances or special functions through combination nanomaterials with polymers has become the focuse in the field of polymer.Carbon nanotubes (CNTs) are one-dimension nanostructural materials with special structures, extremely mechanical strength and well electronic properties.Fe₃O₄ nanoparticles are one of the most popular magnetic materials and have extensive applications in biomaterials field. Through combination such nanomaterials with polymers, we can not only prepare composite materials bearing improved blood compatibility but also provide an effective platform for related researches in other biomedical realms.In this thesis, we prepared Polyurethane/Multiwalled carbon nanotube composites (PU/MWNTs) based on in-situ polymerization and surface modification. Their mechanical properties, thermal properties, surface structure and biocompatibility were investigated. The physical and chemical properties of PU/MWNTs were characterized: thermal behaviors of PU/MWNTs were analyzed by DSC; tensile strength and elongation were measured by universal pulling machine. The biocompatibility of the composite was evaluated through protein adsorption, platelet adhesion and cell growth. The results showed that the introduction of MWNTs did not bring negative effects to the mechanical properties of prime PU, and PU/MWNTs exhibited better biocompatibility compared with prime PU.We also prepared PU/ Fe₃O₄ with the method of solution blending. The disperse situation and the average size of nanoparticles were observed by zetasizer, and the physical properties of the composites were also measured. The results showed that the introduction of Fe₃O₄ improved the mechanical properties of prime PU.