Preparation And Characterization Of Carbon-coated Iron Magnetic Nanoparticles And Its Surface Chemical Modification Research

In the present work, the preparation, characterization and basic application of magnetic nanoparticles were studied. The main objective of this work is to develop a novel magnetic targeted drug carrier. In this paper, carbon-coated iron magnetic nanoparticles and microspheres were prepared with surface chemical modification methods, and some innovational conclusions were received.Firstly, the magnetic carbon-coated iron (Fe@C) nanoparticles with a few layers of graphitic shells were synthesized in a mass scale by laser-induction complex heating evaporation. The samples were characterized by many methods such as transmission electron microscopy (TEM), X-ray diffraction experiments(XRD), Energy Dispersive X-ray Detector(EDX)and it al. It was indicated that the average grain-size of the Carbon-coated iron nanoparticles is 25nm and the thickness of the carbon shells is about 5 nanometers. The nanoparticles have ferromagnetic characteristics with high saturation magnetization (Mz=116emμ/g), low remanent magnetization (Mr=13.1emμ/g) for its high iron content. And its acid resistance and their oxidation resistance are enhanced due to the protection of the compact carbon layer.Secondly, the oxidized magnetic Fe@C composite nanoparticles were prepared successfully by series novel surface chemical modifications. The composite nanoparticles were characterized by means of TEM, XPS, and FT-IR et al. The prime parameters of surface functional preparation is that fully washed with low concentrated hydrochloric acid (HCl, 2 mol·L-1) for dissolving the as-prepared samples at first, and then suspended in a mixture of concentrated H2SO4 (18 mol·L-1)/HNO3 (16 mol·L-1) with the ratio of 3:1 and sonicated in a water bath for 0.5 h. The result of this course was demonstrated by information of FT-IR and XPS. The oxidized Fe@C nanoparticle and 1, 2-ethylenediamine were linked by acyl bond which was demonstrated by the token of FT-IR. The above elementary conclusions offer basis and experimental foundation for magnetic nanoparticles applied in the fields of biology and medicine and so on. Finally, the paper was summarized where it described the current development and expectation of this program and indicated the work plan for the future.