Synthesis And Spectral Properties Of Amide-bonded Bis-porphyrins

The synthesis of bis-porphyrins has become a hot research topic. People have a great deal of concerning and interest in the special structure and spectra properties of bis-porphyrin. So far, the synthesis and photophysical and photochemical studies of bis-porphyrins and oligomeric porphyrins have become a modern important field. As a kind of natural bioactive compound, N, N'-disubstituted urea is an important organic structure unit, and plays an important role in some applications areas, such as antioxidants, pesticides, corrosion inhibitors, and the preparation of pharmaceuticals intermediates.A series of amide-bonded bis-porphyrins were designed and synthesized. And their primary spectra properties were studied.1. The researching progress of bis-porphyrins, especially their usefull synthetic methodologies was summarized simply. Also the action and effect of iodine in organic reactions were simple introduced.2. We designed to use iodine to catalyze the reaction of amino-porphyrins and urea for synthesis of amide-bonded bisporphyrins. The reaction conditions were studied systematically and got the optimized condition. Among them the solvent plays an important role in this synthetic system. We found that DMF is the suitable solvent because of high yield, easy post-processing and convenient monitoring. Based on the optimized condition, 12 amide-bonded bis-porphyrins were synthesized and its structure were confirmed by 1HNMR, Uv-Vis, MS and Elemental analysis.3. The synthesized new amide-bonded bisporphyrins spectra properties were studied preliminally. We found that both the amide-bonded bis-porphyrins and amino-porphyrins had a little red shift in Uv-Vis spectrure. And the absorption of amide-bonded bisporphyrins in the fluorescence is weak, which showed the fluorescence quenching effect.