Study On Preparing, Electrochemical Reduction And Self-Assembled Monolayers Of Ferrocenylthioester

In this report, the progress on the properties and applied research of ferrocenyl derivatives, and the experimental technique, application and development of in-situ FTIR spectroelectrochemistry (FTIRs), derivative cyclic voltabsorptometry was reviewed firstly. A brief introduction on the structure features, mechanism of the thrombosis and research fabricating methods of Self-Assembled Monolayers (SAMs) was given also. Because of the unique optical and electrochemical property, ferrocenyl derivatives have been extensively applied on the study on some chemical and biochemical fields. In this paper, a new ferrocenylthioester was designed and synthesized, and the electrochemical and In-situ FTIR spectroelectrochemical characters were studied. Electrochemical reduction of ferrocenylthioester was conducted and ferrocenylthiol can be obtained. Therefore, SAM of ferrocenylthiol on Au electrode was prepared. Main aspects included in the thesis are summarized as follows:1. Several ferrocenyl derivatives were designed and synthesized. The products were characterized with IR and 1H-NMR.2. Electrochemical behavior of the ferrocenyl derivative was studied by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). In-situ FTIR spectroelectrochemistry technique was used to track the whole electrochemical redox process of the complexes in CH2Cl2 solution. The effects of ferrocenyl derivative structure on electrochemical behavior were discussed. The results indicate that the electrochemical redox process show reversible electron transfer. It is found that the he redox potential of FcC16H11OS move toward positive, which indicated that FcC16H11OS was difficult to be oxidized and easy to be reduced.3. The electrochemical reduction of FcC16H11OS was studied, and cyclic voltammetry(CV) was used to investigate the electrochemical response of the self-assembled mofified Au electrode. It shows that lots of works were tried to get ferrocenylthiol by reducing ferrocenylthioester with chemical reagents and all tests are failure finally, but electrochemical reduction is an effective method to prepare ferrocenylthiol from ferrocenylthioester. The reduction products were ferrocenylthiol and carboxylic acid. The result was confirmed by in-situ FTIR spectroelectrochemistry. The electrochemical chatacter of the ferrocenylthiols self-assembled modified Au electrode was investigated by CV. The experiment results show that the self-assembled modified electrode has a good stability. It takes less time to prepare SAM electrode using the method than traditional method.