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Study On The Preparation And Quality Standards Of Yao Tongkang Capsules

Posted on:2011-12-22Degree:MasterType:Thesis
Country:ChinaCandidate:W L PanFull Text:PDF
GTID:2131330332468712Subject:Drug Analysis
Abstract/Summary:PDF Full Text Request
Lumbar disc herniation is leg pain as the main clinical manifestations of common diseases. Modern medical research shows that: low back pain caused by lumbar disc herniation of nucleus pulposus outstanding addition to mechanical compression, the nerve root and surrounding inflammatory change, is an important factor causing pain. The topics to clinical experience side topics, to facilitate the drug, increased drug stability, the decoction was prepared capsules– Yao Tongkang capsule.Yao Tongkang capsule is Salvia, gracilistylus, DIO, Polygonum, etc. Bawei medicine composed of liver & kidney, blood stasis, Tongluo analgesia. Indications liver and kidney deficiency, blood running smooth, Blood stagnation, context lumbar and leg pain caused by blocked and so the effect is used to treat lumbar disc herniation of pure Chinese medicine. This research project is a reliable efficacy in clinical context, combined with the nature of prescription medicines, take full account of the factors that may affect the extraction, response surface method by boiling process, a scientific and rational experimental design, representative and effective components for the index, then the best technical conditions for the extraction process. Forming process was studied and developed a scientific and reasonable technology conditions.In order to ensure the quality and efficacy of agents, the present study, Thin Layer Chromatography (TLC), high performance liquid chromatography (HPLC), has developed quality standards for Yao Tongkang capsule. Established Salvia, gracilistylus, DIO, Polygonum herbs by TLC method, and the establishment of the finished product and tanshinoneⅡA method for the determination of emodin.The results show that: Yao Tongkang capsule preparation process is simple and feasible, stable, quality control.
Keywords/Search Tags:Yao Tongkang capsule, Lumbar discherniation, Preparation, Quality Standards
PDF Full Text Request
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