The Studies And Applications Of Chemicals From Renewable Resouces In Organic Synthesis

As renewable resource, sucrose, nicotinic acid as well as starch and cellulose which is functionalized are able to be applied to organic synthesis. After sulphonation of sucrose firstly, the sulphonite groups can catalyze the reaction of carbonyl groups protection. It is operated easily to take the place of sulfuric acid which is corrosive and unstable. Indium can be connected to the sulphonite group to form the solid Lewis acid to catalyze Micheal addition with high yields and simple operation. It can be used repeatedly as a heterogeneous and eco-friendly catalysis. Nicotinic acid is non-toxic, harmless and stable which can be used to Krohnke reaction replacing pyridine. It can also be made into a nonvolatile solid perbromide to take part in the reactions of bromination and substitution of bromine which is easy to calculate with high yields of products. The carboxyl group of nicotinic acid can be reduced to aldehyde group to become a capture to catch overdose acylhydrazine in the reaction. Starch and cellulose as a kind of renewable resources exist in the nature widely. After treated with potassium periodate, they turn to be dialdehyde starch(DAS) and dialdehyde cellulose(DAC). They are able to remove overdose amides in the organic reactions as captures to promise the pureness of the products with the easy operation in experiment. It is a new definition of the use of DAS and DAC in organic synthesis.