Studying About 1-Octanethiol Removed By Carbonyl Metal

CO is a new human body signaling molecule, which is similar to the role of NO. Carbonyl metal complex is formed of transition metal and ligand CO, which is a support of CO. The documents point that carbonyl metal release a number of CO molecules with biological activity. It has some potential in cardiovascular drug. Carbonyl metal releasing CO whether can become drug or pre-clinical drug, which depends on the chemical properties of their own and in vivo metabolism of toxicreactions. Therefore, we studied on the chemical properties of carbonyl metal and the reactivity of mercaptan (-SH strong nucleophilic in vivo) for desulfurization by carbonyl metals. We also used FTIR, XPS and XRD to analyse and characterize the desulfurization products. The main content and results as followed:1. Studied on the influence of parameters for desulfurizing process with carbonyl metalsThe Fe(CO)5, Ru3(CO)12 and Co2(CO)8 were used as desulfurizers and by modifying the pressure, time and concentration of each carbonyl metal. The IR, XPS and XRD were used to analyse the products and mechanism. Result:Fe(CO)5 and Co2(CO)8 had very high capacity to desulfurize under atmospheric pressure. The reaction time and temperature for Co2(CO)8, compared to Fe(CO)5, were shorter and lower; Ru3(CO)12 required high pressure in desulfurizing process, as well as higher temperature and longer time. The breakthrough capacity for them was: Fe(CO)5:3450mg/L, Ru3(CO)12:5300mg/g and Co2(CO)8:4800mg/g. The result of XPS showed that desulfurization products obtained Fe3+, Ru4+, Co2+ and S4+.2. Studied on the influence of alkaline additives for desulfurizing processBecause of low breakthrough capacity of Fe(CO)5(3450mg/L),we used H2N(CH2)2OH, C5H5N and (o)CH3C6H4NH2 to improve the reaction. The IR and XPS results showed that H2N(CH2)2OH was the most effective to increase the breakthrough capacity, (o)CH3C6H4NH2 was the worst of them. Too many additives inhibited the removal process of Fe(CO)5. The products contained Fe2+ and S2-, it was probably caused by alkaline additives. The products when adding little or none alkaline additives were still Fe3+ and S4+.