Study On Preparation Procedure Of Zhihong Nano-film

Purpose:In order to better use gardenia red flower in treatment of soft tissue injury formulary eyepit lesions effect, avoid the uneven distribution even traditional film coating layer, unstable shortcomings. This topic according to nanoscale material composition, so that the structure of tiny particles relatively stable, strong penetrating power, easily absorbed by skin to absorb etc; Choose gardenia, safflower two flavour Chinese traditional medicine, match with new nano drug carrier technology to produce nanometer film coating. In the meanwhile more some play efficacy; Simplify the using process, develops the advantages of traditional sa sa, rejected traditional shortcomings. To continue to study Chinese native medicine preparation nanometer technology in the study to lay a solid foundation.Method::through orthogonal test on L9 (3~4) orthogonal test, the optimum extraction gardenia red flower effective components from the best process. Through orthogonal test L9 (3~4), is used to make the proportion of mixed PVA various substrate and mixing PVA and twain - 80 and glycerin mixing ratio. Through the templates make the optimized mixed with nanometer properties PVA. Finally the effective substance extracted with nano coating mix, Zhi red nanometer film made.Result: the determined by the experiment effective components extraction method for medicinal reflux extraction three times, plus eight times the amount of ethanol, every time extracting 75% 1 hour; PVA for a mixture ratio of PVA17-88, a PVA05-88, a PVA124, solvent for 75% ethanol. The 30g PVA match with 4% glycerin and 0.4% twain - 80; Template legal nano membrane, selected the suction filter pressure 0.1 MP, 15nm, aperture diameter 80-100nm alumina for optimum technological conditions of nanometer template for.Conclusion: preparation of nanometer film Zhi red than traditional film more bearable, softer, resistant to friction, and nature is stable, facilitate drugs are effective components are skin. Have basic can achieve the desired goals.