Preparation Of Gold Nanoparticle Modified Electrode And Its Application In Epinephrine And Glucose Electrochemical Analysis

In resent years, much more active attention has been devoted to gold nanoparticles modified electrode. Electrode, which surfaces modified with metal nanoparticles can be characterized and applied by electrochemical chemical method, and thus prepared surfaces have been applied to the electrochemical catalysis successfully. In order to make full use of these characters of gold nanoparticles, the substrate is very necessary. The metal nanoparticles modified on the electrode surfaces also could be applied in electronic communications as well as the its conductivity. Attachment of nanoparticles to an electrode is an important procedure in electrode modification. There are numerous approaches to fabricate nanomaterials on electrode surfaces, depending on the exact material and substrate. The modified electrodes usually exhibit different electrochemical and electrocatalytic characteristics even if there is a slight change in the modification procedure. Therefore, it is necessary to discover different nano electrode materials as well as novel attachment approaches. Herein, we would like to present a novel electroless method to fabricate a gold nanoparticles-modified electrode without using peculiar binding molecules.In this paper, the preparation of gold nanoparticles modified electrodes by using the method of electrochemical deposition and seed mediated growth has mainly demonstrated. Also, electrochemical catalytic characteristics for epinephrine and glucose oxidation were observed for the gold nanoparticles modified electrode. All the relative studies are outline as follows:(1) First of all, it demonstrated the preparation of electrochemical deposition gold nanoparticles on indium tin oxide glass and the process of cysteine self-monolayers over gold nanoparticles.It stressed the electrochemical selection determination of epinephrine in presence of sodium dodecylsulfate,which is also the innovation points of the research. Gold nanoparticles modified electrode, which electrochemical activity has been enhanced, can selectively detemine epinphrine in presence of interfering compounds with a low limit of detection.(2) In the second part, it presented the preparation of seed mediated growth of gold nanoparticles on indium tin oxide(ITO) electrodes. The first step was the electrochemical deposition, which attached the gold nanoparticles, called gold seeds, on the surface of the glass. Then, the ITO was immersed in the gold growth solution for a period. The size of the gold nanoparticles could be controled by changing the length of the time. The modified electrode has more attactive electrocatalytic properties and application perspectives. Also, it can worked as Surface-Enhanced Raman Scattering(SERS) active substrate bacause of its Raman acivity.(3) In the third part of the paper, the seed mediated growth of gold nanoparticles on the ITO for non-enzymatic detection of glucose was reported. Au nanoparticles dence attachement on the ITO provides more active surface area and thus enhanced electrocaltalytic performances for the glucose electrochemical oxidation.These would improve the selectivity of the electrode, which is of great important for the non-enzymatic detection of glucose. Hence, it was of both fundamental and application interests to evaluate effects of the interfering species.