Preliminery Studies On The Compounds With Antimicrobial Activity From Anabasis Aphylla L. In Xinjiang

Progress on plant antimicrobial compound research and plant resources with antimicrobial activities in Xinjiang of China have been reviewed in this thesis. Anabasis aphylla L. is a hungriness species with its great biomass in Xinjiang. To be best of our knowledge, study on its antimicrobial activity has not been reported in our country.Two new acrylamide alkaloids, (E) - N - (4 - hydroxyphenethyl) - 3 - (3 - hydroxy - 4 -methoxyphenyl) acrylamide (compound 1) and (Z) - N - (4 - hydroxyphenethyl) - 3 - (3 - hydroxy - 4 -methoxyphenyl) acrylamide (compound 2), as well as two known compounds (+)-syringarensinol (compound 3) and schisandrin (compound 4) were isolated and identified from the aerial parts of Anabasis aphylla L. by the methods of phytochemistry and activity screening. Compounds 3 and 4 were separated from A. aphylla for the first time.Phytopathogenic fungi and bacteria were used in activity screening. It was found that both compounds 1 ,2 and 3 with their concentration 10ug/ml and 100ug/ml had no activity to inhibit spore germination of Magnaporthe grisea., but to promote the growth of germtube. Their effect on appressorium formation of M grisea are in the studying. Schisandrin had an inhibition to mycelial growth of Botrytis cinerea, Pythium aphanidermatum, M. grisea, Fusarium graminerarwn,Fusarium oxyspcrum f.sp. niveum.Study on antimicrobial compounds from A. aphylla L. will benefit for providing leader compounds of chemical synthesis, for studying structure-activity relations, for studying the phytochemistry taxology, as well as for development and utilization of plant resources in Xinjiang of China.