| BackgroudThe theory of "vital Qi"is unique in TCM, in which vital qi plays a critical role in the course of disease. The "rousing" rule based on the " vital Qi "theory can be a good guide in clinical, and now its unique advantages has been gradually highlighting. in Critical Care Medicine both Western and Chinese medicine. Nowadays, in our growing aging society, The number of elderly people in ICU increasing, so that the research of "rousing" based on the " vital Qi "theory is imminent. However, since the disease is so complex and the "vital Qi" of diseases can not be quantified, research of " vital Qi " theory it is difficult to get rid of the perceptions of clinicians. Therefore, this study tries to Dengue Fever-this pathogen clear, relatively fixed duration, similar to the symptoms of infectious disease among individuals as a carrier to study the effects of the disease righteousness difference. Therefore, with the carrier of Dengue Fever which has clear pathogen, relatively fixed duration, similar symptoms among individuals, this study tries to study the effects of the impact of "vital Qi" difference on disease.Objective:This study investigates the effect of differences in the level of " vital Qi " on diseaseMethodsAccording to the diagnostic criteria on "Dengue treatment guidelines (2nd edition in’2014) ", this study screened 134 patients met the diagnostic criteria of Dengue from patients presenting to the emergency department in the First Affiliated Hospital of Guangzhou University of Chinese Medicine and Department of traditional Chinese medicine in the Eighth People’s Hospital of Guangzhou City, during September to November in 2014 when happened the outbreak of dengue fever. ①We analyze the basic statistics of the DF patients enrolled in the study. ②For selected patients, we grouped them to four groups by age reffered to the physiological developmental cycle recorded on Suwen ancient naive theory and Lingshu The natural life. The groups were:age≤32,32<age≤48,48<age≤64 and age>64 years old. Then, we study temperature peak difference, different duration of admission days, different level of WBC and PLT on the 6th,7th,8th days, and different clinical characteristics of rash among them.③According to the temperature for clinical classification, the patients included in the study were divided into 4 groups according to the peak temperature:T≥40℃,39℃ <T<40℃,38.5℃<T≤39℃,and T≤38.5℃.And we study different duration of admission days, different level of WBC and PLT on the 6th,7th,8th days, and different clinical characteristics of rash among them. ④According to the different duration of days of admission, the patients with DF were divided into 2 groups:admission course≤5 days group and admission course≥6 days group between the two groups of groups, and WBC, PLT difference on the incidence of 6th,7th,8th days were analyzed. ⑤According to that rash appeared or not, patients with DF were divided into 2 groups, and we studied WBC, PLT difference of the 2 groups of 6th,7th, and 8th days of onset. Based on the data using SPSS 21 statistical software for statistical All data were analyzed statistically by SPSS 21.0 software.ResultsIn this study, DF patients aged between 15~86 years old, with the average age of 46.80±19.46 years. Since male were 73 cases, and female 61 cases, the male to female ratio was 1.2:1. This study shows that the body temperature of patients DF peak at 37.6～40.8 DEG C, with the average temperature 39.22±0.65 C. Patients with peak temperature higher than 39 degrees occupy 76.3%. The average duration of DF patients on admission days was 6.10±1.79 days.This study shows significant difference between mean peak temperature of different age groups of patients (P=0.000). Statistical differences of mean temperature peak between patients age>64 years and the other three groups. While there is no linear relationship between age and body peak temperature (the value of P=0.359) This study shows that, there was significant difference of whether a rash between different age groups (P=0.001). A rash frequency from high to low age group was 32< age< 48, age< 32,48< age< 64, and age> 64 years old group., there was no significant difference between the mean admission course days of patients in different age groups (P=0.257). Mean time of course duration on admission was 6.10±1.79 days. The mean course days of four age groups were 6.39 days,6.28 days,6.03 days, and 5.66 days.This study shows no significant difference of skin rash between different groups of peak temperature(P=0.190). A rash of frequency from high to low temperature groups as temperature group of less than 40 DEG C, temperature group of 39.1~39.9 DEG C, temperature group of 38.6~39 DEG C, and temperature group of<38.5 DEG C.This study shows that, admission course≤5 days group has a higher mean value of PLT than admission course≥6 days group on 6th,7th, and 8th day of the incidence, and the difference has statistically significant difference(P values were P=0.002, P=0.000, P=0.000). But there was no significant difference between the two DF groups of their average WBC on the incidence of 6th,7th, and 8th day. Although in the course of 6th,7th, and 8th, patients with dengue fever were hospitalized, their PLT still showed a downward trend.ConclusionsDengue virus are generally susceptible in different age groups, especially in adults, and the incidence has no difference between different genders. Patients infected with Dengue virus will appear after the onset of symptoms of fever, mainly hyperpyrexia. Patients suffering from Dengue fever were mostly hospitalized after more than 6 days (including 6 days) (see Table 4). Although in the course of 6th,7th, and 8th, patients with dengue fever were hospitalized, their PLT still showed a downward trend, while the WBC showed a increasing trend and reached the normal range on the eighth day, with no obvious correlation with the hospital treatment.Age group of DF patients accepted earlier hospital treatment than the younger group, and their temperature peak were lower than younger age group. Even elderly DF patients accepted earlier hospital treatment, their PLT value was still lower than the younger patients in the course of sixth, seventh, and eighth days. Whether DF patients had rash is closely related to their age, and the younger group rash incidence was significantly higher than the elderly group. DF patients’ skin rash also had correlation with peak temperature:the higher the peak temperature, the higher rate of rash. These differences on clinical characteristics depended on the differences of Vital Qi level. Since younger patients had more abundant Vital Qi, they had a later hospital treatment time, higher peak temperature, higher incidence of rash, and higher PLT value on the incidence of 6th,7th, and 8th day.Dengue fever has no specific therapy, but patients can be well benefited from early admission and symptomatic treatment comprehensively. The temperature peak in exogenous disease could also reflect the "Vital Qi" levels to a certain extent. |
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