Changes Of Syndrome Score Of Blood Stasis Syndrome In Perioperative Period Of Cervical Spondylotic Myelopathy And Observation Of Related Factors

Purpose:To investigate the characteristics in blood-stasis pattern in perioperative period of cervical spondylotic myelopathy (CSM) and to discuss the mechanism of how the surgery impacts on the changing of the patterns and explore the treatment based on differentiation of pattern in the perioperative period of CSM, by using the quantitative diagnostic criteria for blood-stasis pattern; to deepen the clinical application of blood-stasis pattern theory in CSM, as well as to improve the clinical efficacy.By effective intervention or control on blood-stasis pattern, prevent and treat the complications such as stress ulcer and venous thrombosis of lower extremity actively; to lay the foundation of application of blood-stasis theory on bone diseases.Methods:Patient sample:A total of 30 consecutive patients with cervical spondylotic myelopathy operated on during a 4-month period (January 2014 to May 2014) formed the study group. Research method:The participants in this study underwent anterior cervical discectomy and fusion (ACDF) for cervical spondylotic myelopathy before and after surgery,The scales of blood-stasis pattern were evaluated, the PLT and FIB were recorded, which were analyzed by SPSS 19.0.The change of blood-stasis pattern before and after the surgeries,the relationship among the related indication can be understanded,then draw the corresponding conclusion.Results:the relevance between the scales of blood-stasis pattern and the number of involved cord gaps, the platelet count and the fibrinogen content is present in this study. The difference of scales between 3 days after the surgery and 1 day before the surgery was also relevant with the course and the number of involved cord gaps. There was a significant difference in the scale of 1 day before the surgery and 3 days,7 days after the surgery, as well as 3 days after the surgery and 7 days after the surgery(p<0.05). There was also a significant correlation between the platelet count and fibrinogen content in 1 day before surgery and 7 days after the surgery(p<0.05).Conclusions:This study indicates that the ischemia of spinal cord can be ameliorated by the intervention of operation for the treatment of CSM,which may contibute to improve the performance of systemic blood-stasis pattern in patients.Some of the blood-stasis syndromes could be relieved while the blood supply of the spinal cord is improved. We revealed the characteristics of the blood-stasis pattern changing during the perioperative period of CSM. The assessment of the severity of syndrome guides the chosen of suitable traditional Chinese medcine and chinese patent medicine. The shortcomings of this research were the short of study’s period on the change and its law of pattern before and after the perioperative period, on the change of the blood-stasis pattern after the application of blood-activating drugs associate with operation. We merely compared the change of the blood-stasis pattern due to the insufficient number of subjects. Panel discussions, large examples and further observation and summary are needed to emphasize the effects of the surgery.