Study On Registration Of Angina Pectoris With Coronary Heart Disease By Danhong Injection

Objective:This study applies the real world research methods, multi clinical centers marked the information of Danhong injection in treatment of coronary heart disease, analysis ing the efficacy and safety of Danhong injection in treatment of angina pectoris of coronary heart disease, and comparing the efficacy and safety of unstable angina and stable angina pectoris.Method:Take the real world research ideas, in the form of registration, multi clinical centers marked the information of Danhong injection in treatment of coronary heart disease, Once the patients began to be selected, must be continuously enrolled,you can’t pick and leak selected objects, recording the real medical environment, detailed record the use of Danhong injection in the treatment of patients with coronary heart disease in general demographic data, clinical data, heart attack frequency, duration of angina pectoris, nitroglycerin usage, symptoms and signs of change, TCM syndrome curative effect, the doctor and patient satisfaction, the incidence of adverse events, serious adverse events. Divided into two levels to analysis its efficacy and safety, the first level is the overall effectiveness and safety of Danhong injection in the treatment of angina pectoris of coronary heart disease; the second level is the difference and safety evaluation of Danhong injection in treating unstable angina and stable angina curative effect of stratification.Result:Demographic data and information:The patient has follow characteristic:male, Han nationality and non manual workers,with hypertension. the mainly symptoms of patients is chest pain, chest tightness, shortness of breath, palpitations, fatigue, and the most common syndromes is blood stasis syndrome.the baseline data of Stable angina and unstable angina is parallel (p>0.05). Coronary angiography is the mainly diagnostic methods, especially to the unstable angina2. Effect:2.1 The overall effectpatients immediate pain relief time is 2.42 minutes. Compared with before treatment, The frequency of attacks is average decreased 3.47 times, the Angina cordis decreased 4.71 points/time, dosage of nitroglycerin average decreased 2.41 tablets per week, average 3.16 reduction in angina pectoris integral. Traditional Chinese medicine t clinical control rate was 19.4%, total effective is 61.1%, the total efficiency is 98.1%.2.2 Grouping effectBefore and after the treatment, the unstable angina group in The frequency of angina pectoris、Angina cordis. Angina pectoris integral is Decreased more obviously.3 SafetyDuring the use of Danhong injection,1 patients has adverse events, accounted for 0.3%, the symptom is mild chest pain. No statistical significance between unstable angina and stable angina group,(p>0.05).Conclusion:1. Danhong injection in treatment of Angina pectoris is effective. It can reduce the attack of angina pectoris, shorten the duration of angina pectoris, reduce the integral, improve angina symptoms. Compared with stable angina, Danhong injection has better curative effect on unstable angina pectoris.2 Danhong injection has some side effects in clinical, but it is lower.