Discussion On The Scientific Connotation Of Spleen As Based On Multivariate Statistical Analysis Of Modern Literature

Purpose: Zang-fu theory is the core part of the basic theory of TCM, has become many scholars to research hot spot in recent years, the nature of the zang-fu research is one of the focus and difficulty. Spleen is an important component of the theory of zang-fu,as the documents of the spleen is growing, but investigate its scientific connotation is still not determined, Establishing the spleen theory related modern literature database, is used to further clarify the spleen as scientific connotation. Data mining analysis method has been widely applied in the field of traditional Chinese medicine, can be more intuitive, objective help us describe inherent law between things, makes the study of the spleen as nature more deeply.Material and method:B y means of literature metrology, multivariate statistical analysis and data mining method, the system disease, Chinese medicine syndrome, spleen dysfunction as relevant frequency change indexes, cluster analysis, For high frequency syndrome and spleen dysfunction as related change index association rules analysis, to discover the spleen as the scientific connotation and law of theory.Results:1. With the literature grows, there is a growing trend to nearly six years of growth is particularly prominent. Description of the doctrine of the spleen as research is under continuous development and rich.2. Documents in the database according to the classification of disease system and through the frequency statistics analysis, the spleen as modern literature is given priority to with digestive system diseases, and significantly higher than the other system diseases. Followed by the kidneys and urinary tract disease, liver disease, etc.3. The database according to the type of syndrome classification in the literature, through the frequency statistics analysis, to the spleen as a separate type of syndrome type than other combined viscera, again to pixu(spleen deficient) in the spleen as a separate card type, temper,spleen Yang deficiency, spleen Yin deficiency, such as wet trapped pixu(spleen deficient) as the main syndrome types.4. Extraction index of literature is contained in the database, statistical analysis and induction,sorting, distribution characteristics, found that the index distribution related to digestion,immune, blood, endocrine and nervous system, cell signal transduction and cell apoptosis and energy metabolism, etc.5. By cluster analysis to the spleen dysfunction as related change index is divided into four more meaningful combination.6. High frequency through the analysis of the association rules syndrome and spleen dysfunction as index were negative related changes, which does not apply to the statistical analysis method.Conclusion:1. This study has established the spleen dysfunction related literature database.2. Through frequency analysis, clustering analysis can directly display the spleen as the distribution regularity of the literature。3. Through the analysis of the association rules can not interpret the spleen as scientific connotation。...