Distribution Of Antibiotic Resistance Of Animal-Origin Campylobacter Jejuni

Since the 1970s, C.jejuni has been generally considered as the main cause leading to the intestinal infection throughout the world. Campylobacter jejuni widespread in the animal gut, intensive use of antibiotics in aquaculture production, the inevitable animal Campylobacter jejuni in the development of resistance, and this resistance can be adopted by animal-derived food processing and consumption, etc. - people.Antibiotics are used when Severe infection and delayed enteritis occurred. With widely use of the antibiotics, the Antimicrobial Resistance of C.jejuni is worldwide focused, while few researches have been reported in China.In our study, 47 C.jejuni was isolated from 203 fowl appendix contents, and Antimicrobial Resistance of these bacterium was tested by disk diffusion technique. The result indicated that 31.9% c.jejuni demonstrated resistance to Ciprofloxacin, the high level of resistance seen were to ampicillin (85.1%), Clindamycin (83.0%), and erythromycin (83.0%), and c.jejuni were more sensitive to furaxone (85.1%)and gentamicin(74.5%). Combined resistance was observed on 89.4% c.jejuni.99 C.jejuni was isolated from 294 swine appendix contents, and Antimicrobial Resistance of these bacterium was tested by disk diffusion technique. The result indicated that 22.2% c.jejuni demonstrated resistance to Ciprofloxacin, the high level of resistance seen were to ampicillin (86.8%), Clindamycin (84.8%), and erythromycin (82.8%), and c.jejuni were more sensitive to furaxone (84.8%)and gentamicin(70.7%). Combined resistance was observed on 90.2% c.jejuni.Chicken and pig-resistant Campylobacter jejuni status of the comparison results indicate that, chickens and pigs source of Campylobacter jejuni-source Resistance of the overall situation of the difference was not significant. Chicken source of Campylo -bacter jejuni furazolidone, vancomycin, tetracycline, cefradine, ciprofloxacin, erythro -mycin, gentamycin, clindamycin and ampicillin resistance, respectively : 8.5%, 100 %, 55.3%, 25.5%, 31.9%, 83.0%, 17.0%, 83.0% and 85.1%, than the general swine Campylobacter jejuni higher, the difference was not significant. The different animal source of resistance of Campylobacter jejuni there was no significant difference.Different origin chicken source resistance of Campylobacter jejuni status of the comparison results indicate that, Jiangsu Nantong, Jiangsu and Zhejiang Jinhua Haimen isolated from chicken Campylobacter jejuni on nine kinds of antibiotics have different levels of resistance to vancomycin, erythromycin and ampicillin resistance of 100%. Haimen, Jiangsu, Zhejiang and Shanghai Chongming Wenling, Jinhua, such as the strains were ampicillin of clindamycin and showed high resistance, respectively, 90% and 100%. Different origin swine Campylobacter jejuni resistance of the comparison results indicate that the situation in Shandong Xinxian isolated from pigs Campylob -acter jejuni on nine kinds of antibiotics have different levels of resistance to vancomy -cin, erythromycin, clindamycin and ampicillin resistance of more than 80%. Mengjin, Henan and Anhui Huaibei isolated from the source of Campylobacter jejuni pig except cefradine from eight kinds of antibiotics have different degrees of resistance to ampicillin resistance of 100%. The results showed that animal-derived resistance of Campylobacter jejuni marked geographical differences.