IntroduceSilicosis is one of the most serious occupational diseases by far. It is unclear how silicon dioxide dust can result in pulmonary fibrosis and silicosis. The mechanism of silicosis is furthering to the molecular level on the basis of the epidemic research. The research is focuses on the effect of biology active content, the hereditary susceptivity, and the mutant of the gene. Mastering the mechanism of silicosis on the level of molecule will assist to prevent and therapy silicosis in itself.Gap junctions are protein channels found at the juxtaposition of the cell membranes of 2 adjacent cells. They serve as conduits, permitting the exchange of small molecules ( |