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Experimental Study On The Pharmacodynamics Of GuanLuoTong Tablet In Treatment Of Rheumatoid Arthritis

Posted on:2003-06-05Degree:MasterType:Thesis
Country:ChinaCandidate:L H ShengFull Text:PDF
GTID:2144360065961065Subject:Pharmacy
Abstract/Summary:PDF Full Text Request
GuanLuoTong Tablet contains Siegesbeckia Herb, Stem of Orientvine, Red Peony Root, Mulberry Twig, Honeysuckle Stem, Stem of Chinese Starjasmine, Stem of suberect Spatholobus, Root-bark of Showy Eriolaena, Root of Fourstamen stephamia, Fruit of Floweringquince, Chinese Angelia, Root of pale Bittersweet, Scorpion, liquorile Root, which has the effect of invigorating blood circulation and dredging channels and collaterals, eliminating dampness and dispelling cold. It is mainly used to treat Rheumatoid Arthritis in clinic. Some experimental study on the pharmacodynamics of this tablet was done in this thesis. The results show that: This tablet can decrease the rat's footpad swell induced by Freud's, inhibit the permeability of the blood capillary in inflammatory joint and decrease the 11-2 level in serum while increasing the rat's body weight, (2) It can lower the rat's temperature and the permeability of the blood capillary in inflammatory joint induced by collagen and inhibit the delayed type hypersensitivity,It can lower the stickiness of full blood and the accumulation of erythrocyte obviously inblood stasis model rats,lt can inhibit the formation of hemolysin and decrease the index of carbon granule clearance in mice, It can lower the permeability of celiac blood capillary and inhibit the granulomatous hyperplasia by sc cotton ,It can inhibit the pain induced by acetic acid and raise the pain threshold value of heat stimulation.Finally, we can infer from the experimental results: Tablet of Guanluotong has obvious effect of anti-inflammation, invigorating blood circulation, relieving pain and inhibiting immunologic function, and can be used as an effective Chinese Medicine to treat Rheumatoid Arthritis.
Keywords/Search Tags:GuanLuoTong Tablet, Arthritis/Freunds', Arthritis/Collagen, anti-inflammation, invigorating blood circulation, relieving pain, immunologic function
PDF Full Text Request
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