Effects Of Percutaneous Balloon Mitral Valvuloplasty On P-wave Dispersion And The Analysis Of Relative Factors

Objective to estimate the effects of percutaneous balloon mitral valvuloplasty on p-wave dispersion(Pd) and other electrocardiographic variables and investigate the association of them with echocardiographic and hemodynamic parameters.Methods 31 patients with rheumatic mitral stenosis who were candidates for PBMV were selected for the study.12-lead electrocardiogram and echocardiogram were recorded for each patient 1 day before PBMV and repeated at the 24-48 hours and 4-6 months after PBMV,Pd,maximum and minimum P-wave duration(Pmax,Pmin),left atrial diameter(LAD),mean mitral gradient(MMG),mitral valve area(MVA) were measured respectively.During PBMV,mean left atrial pressure(MLAP) was recorded by balloon catheter before and after inflation.Results The Pd,Pmax,Pmin after PBMV were significantly lower than those before PBMV,there were also statistically significant decrease 4-6 months than 24-48 hours after PBMV.Statistically significant improvement in LAD,MMG,MLAP,MVA was achieved after PBMV.In simple regression,Pd,Pmax were weakly related to LAD,MLAP,MVA before PBMV,but in multiple regression,only Pmax was related to LAD.There was no Statistically significant correlation between the decrease inPd,Pmax,Pmin and the improvement in LAD,MMG,MLAP,MVA at the 24-48 hours after PBMV .Conclusion The continuous decrease of Pd,Pmax,Pmin and the improvement in echocardiographic and hemodynamic parameters after PBMV showed the good results in PBMV for patients with rheumatic mitral stenosis,but the changes of electrocardiographic variables were not parallel to the improvement in echocardiographic and hemodynamic parameters after PBMV.