The Simulation And Visual Research On Bioceramic Degrading Process In Vivo

As one of the best restoring materials for bone impairment, 3-TCP can cause or permit neighboring bone organization to grow. At the same time, it can gradually degrade and be replaced by new bone organization, thus reaching the aim of curing impaired bone. By studying the mechanism of B-TCP's degradation and ossification, completing three-dimensional simulation software through C++ and ACIS and showing the dynamic degradation process on screen, we can not only observe and investigate the changing process after the material's implantation in human body generally and carefully, but also analyze its degradation capability, thus providing theoretical bases for developing and exploiting new functional materials.Through the above research, we get the conclusions as follows:1. After deeply realizing the material's degradation mechanism, this article conducts further research on the two-dimensional model about material's degradation process. It takes the material's degradation characteristics into account and construct three-dimensional simulation model which corresponds to the actual degradation process in human body, by using Monte Carlo method. Besides, it verifies the rationality of simulation model by computation on degradation extent and relevant parameters.2. We investigate the relationship between material crystals' growth and degradation. After studying the growth model of multi-crystals material, we find that material's degradation process is crystals' gradual shrinkage and being swallowed under complex physiological environment, until it disappears completely and is taken place by new organization. Such a process happens to be reverse to that one of crystals' growth. So these two processes share some internal relationships on construction of model and realization of simulation algorithm.3. By applying crystals' growth theory to construct material degradation model, we realize the algorithm and process simulation on biological material degradation. The simulation result shows that there appear micro-structure changes along the border of material and bone. It proves the conclusion that new bone firstly grows along border.4. The three-dimensional visual simulation model constructed in this article can obtain sections flexibly. By analyzing these sections and comparing simulation result to experimental outcome, we can prove the validity of the simulation model.