| Islet cell tumors are a relatively rare tumor occur in the pancreas. Although relatively rare, the tumors present an important challenge to the clinician because of their protean manifestations and potential lethality. Early diagnosis is essential and depends on recognition of the classic and variant clinical syndromes followed by confirmation of elevated peptide levels by radioimmunoassay. Localization and staging of the tumors are important because they way be small and occult. Computed tomography, visceral angiography, endoscopic ultrasonography are the most useful preoperative imaging techniques. Surgical exploration that includes intraoperative ultrasonography remains an essential localization technique for occult tumors. Surgical procedure is necessary, the earlier the better. In this review article, all clinical aspects of islet tumors are examined .Objective: To study the diagnosis and treatment of islet cell tumor retrospectively.Methods: The seventeen cases with islet cell tumor from 1998 to 2002 year in the second Affiliated Hospital of Medical college, Zhejiang University were studied, with a mean of 40 years (range, 17-70). CT, B-US and visceral angiography were performed in 15, 16, 2 cases seperatively; and 14 patients were underwent a resection operation. There were tumor excision 7 cases, distal pancreatectomy plus splenectomy 5 cases, pancreatoduodenectomy 1 case, tumor excision plus subtotal gastrectomy, Billroth II and Bancroft operation 1 case respectively.Result: There were 11 cases confirmed to benign, 3 cases malignant; The mass in the head of pancreas was 4 cases, in the body 5 cases, in the tail 5 cases and a mutile insulinoma. All 14 cases had a good prognosis except two pancreatic fistula in 2 cases and incision infection in 1 cases.Conclusion: All the patient with islet cell tumor ought to resect mass if can. |
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