The Experimental Study Of The Cellular Compability Of The Porous Pure Titanium Implant

After the implant has been placed in to the alveolar ridge, two different kinds of interface may form. One is osseointegration interface, the other is fibro-osseointegration interface. Among them the former is better. Nowadays, many kinds of implant systems with different shapes come into clinic use. Among these systems, some of them use the surface-activation. Although they are different in pattern, all of them try to form osseointegration after the implantation. Thus successful rate of the implant surgery and the restoration may be improved.The objective of this study is to draw lessons from the porous structure of the natural bone and other kind of implant which also contain porous structure or coral-shape structure, such as HA and some high-polymer materials, and try to make a new kind of implant which contains porous three-dimensional structure. In that way ,the new implant may have the similar construction to the natural bone, thus the newly formed bone may grow into the deep part of the porous implant, and fill in the whole implant ,and in the last a better osseointegration may form.In this experiment, we sinter the titanium particles into a designed shape in the powder metallurgy method. In that way ,a new implant with continuous porous structure constructed . And then we experiment the implant with osteoblast in vitro to study the cellular compability of the implant. The result shows1. The osteoblast grows well on the surface of the implant, and forms three-dimensional structure .As time progresses, some cells grow in to the porous structure .2, Compared with the polished titanium plate, the porous structure improves the RCR% of the osteoblast, especially the 800um group.All the results show that the cellular compability of the new implant is good. From the result, it is reasonable to make an implant with porous structure. It is beneficial for the attachment and spreading of the osteoblast on the porous implant, and lead to the bone formation after the implantation. Thus it may be a good attempt.