| Objective: To evaluate the bone implant interfaces of two kinds of implants with different surfaces in different time in vitro. Materials and Methods: CDICand ITI solid-screw cylinder pure titanium implants were selected and implanted in the regions of mandibular posterior molars of rhesus monkeys. The bone implant interfaces of 1 month, 2 months, 3 months and 1 year were evaluated respectively through oral examination, X-ray inspection, light microscope and scanning electron microscope (SEM) observation and elementary analysis using electron probe. Results: None of the implants was loose. Soft tissue around implants appeared no inflammation. There was not apparent transparent shadow around the implants interfaces in X-ray photos except little angle-shaped absorption in neck region of CDIC implants of one-month was showed. New growing bone was observed around implants of one-month through light microscope and SEM. More bone growing around ITI implants were seen than that around CDIC implants except the interfaces of one-year. Ions of Ti, P, Ca filtered each other, ions of P, Ca filtered towards implants and appeared higher density and closer with time passing. The density of Ti filtered from ITI implants in different time was respectively higher than that from CDIC implants. Conclusions: The two kinds of implants have fine biocompatibility. The osseointegration of ITI implants is excelled than that of CDIC implants during three months after implanting without loading, The interfaces bone formation between ITI and CDIC implants of one year after implanting without loading has no difference. Ions of Ti, P, and Ca filter each other in the implant interface and the densities in tissue are increased with time passing. The phenomena of Ti filtered of ITI implants are more apparent than that of CDICimplants without leading inflammation observing by light microscope. The method of grinding slices with implant and tissue explored in the study is reliable.
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