| Objective: To study the correlations between microelements: Fe, Zn, Ca, Pb and chronic rickets, the relations between them and the clinical meaning significance were discussed. The early curing and intervening testimony was provided so that to improve the body quality of children.Methods: The blood contents of Fe, Zn, Ca, Pb, bone alkaline phosphatase and X-ray of wrist haye been detected in the 42 cases of children with chronic rachistis, and 33 controls of children without this disease, who came from child health care clinic centre in Shanxi Maternal and Children Health Care Hospital from January 20, 2002 to February 29, 2003. The relations between the determined results and chronic rickets wereanalyzed by Single-factored logistic regress, multi-factored logistic regress, and covariance analysis.Results: The rank sum test showed that the contents of microelements: ferrum, zinc and calcium in blood were markedly lower in test group than that in the control group, which Z values of ferrum, zinc and calcium were 1. 05, 3.18 and 3.00, respectively, and the P values were less than 0.01, but the levels of Pb in blood were opposite that the test groups were higher the control groups, which the z value was - 3.94 and P value was less than 0.01, too. The level of alkaline phosphatase was higher in chronic rickets group than in the control groups, which the z value was 4. 18 and the P value was less than 0.01.The economic conditions affected the incidence of chronic rickets. There was significant difference between the test group and the control group (Z=-4. 4014, p<0. 01). The x2 test indicated that the levels of zincand calcium were lower in the test groups than the control groups in blood, which the x2 values were 10. 32 and 14. 21, respectively, and the both P values were less than 0. 01. Fisher's exact test showed that the levels of ferrum in blood were lower in the test groups than the control groups (P=0,000048). The Fisher' s exact test indicated that the incidence of chronic rickets was higher in the child group by breast feeding than by cow's milk and mixed feeding (P P=l. 486*10-13). The incidence of iron deficiency anemia was higher in the chronic rickets groups than in the control groups ( x2 =10. 397, P <0. 01) , which the incidence were 16 (38. 1%) and 2(6. 06%), respectively. There were other effective factors such as adding calium, adding vitamine D, history of chronic rickets and deficiency zinc, the mounts of milk, blood Hb, eggs and fowls, bean , bean ware and the ways of feeding. The incidence existed significant differences between in the chronic rickets groups and in the control groups, which the values ofadding calium and vitamine D, history of chronic rickets and deficiency zinc, the mounts of milk, blood Hb, eggs and fowls, vegetables , bean and bean , and the ways of feeding were ( x2 =18.52, P<0.001 ) , (Fisher' s exact Test, P<0. 01), ( x 2 =49. 844, P<0. 001), (x2 =12.28, P<0.01), (x2 =49.844, P<0.01), Hb(x2 =9. 27,P<0. 05), (x2 =12.09, P<0. 05 ) , (x2 =24.35, P<0. 05), (x2=49. 38, P<0. 01), (Fisher' s exact Test, P<0.001 ) , respectively. The results of the rank correlation of Spearman showed that there was positive correlation between the deficiency ferrum and zinc, serum iron and calium, and serum calium and zinc (P<0. 05) , which the correlation coefficiencies were r=0. 41, r=0. 425 and r=0. 35, respectivel; and there were negative correlation between the deficiency ferrum iron and Pb, serum calium and Pb, and serum zinc and Pb (P<0. 05) , which the correlation coefficients were r=-0. 326, r=-0. 395 and r=-0. 432, respectively. The results of Logistic s regress analysis showed that thebreast feeding, eating bean and bean ware, and the content of serum calium were the protecting factors. The history of chronic rickets was the dangerous factor of chronic rickets.Conclusion: 1. The children with chronic rickets were short of zinc, ferrum and calium, and rich in over Pb. The deficiency of zinc, ferrum and calium affected the absorption of vitmin D so... |
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