| Objective: To evaluate adrenal, ovarian steroidogenesis and INS and ovulation rate and pregnancy rate before and after cyclic treatment with Tiaojingzhuyuntang and CC in women with polycystic ovary syndrome (PCOS).Design and Methods: Two groups of PCOS women, each containing twenty-six women with PCOS, were evaluated before and after treatment(3~6 weeks) with Tiaojingzhuyuntang combined with CC, with respect to serum steroid levels of LH FSH, LH/FSH, T, FT, INS.Results: In group A, 92.31% of the women had a significant improvement in menstrual cyclicity, and pregnancy rate was 69.23% with significant melioration in shenyangxu symptoms. In group B, 84.62% of the women were observed a significant improvement in menstrual cyclicity with improved pregnancy rate (42.31%). But no significant melioration in shenyangxu symptoms were found.Conclusion: Higher levels of LH, FSH, T and FT are important biochemical features in PCOS patients. Tiaojingzhuyuntang can regulate the unbalanced inner- enviroment in PCOS patients from the points of reproduction and metaboliam and then recuperate their reproductive function and balance their energy metaboliam. The deficiency of kidney and the phlegm stasis are responsible for the pathology of PCOS from the point of view of Chinese traditional medicine. |