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The Value Of Blood Sugar And Diabetes Mellitus In Assessing The Activity And Long-term Prognoses Of Acute Coronary Syndrome

Posted on:2005-08-09Degree:MasterType:Thesis
Country:ChinaCandidate:S Y YuFull Text:PDF
GTID:2144360125451717Subject:Internal Medicine
Abstract/Summary:PDF Full Text Request
ObjectiverTo reveal the value of blood sugar(BS) and 2-type diabetes mellitus(DM) in assessing the activity and long-term prognoses acute coronary syndrom. Metheds: 165 patients were divided into four groups: control group,stable angina pectoris group(SAP),unstable angina pectoris group(UAP), acute myocardial infarction group(AMl).All patients had been undergone coronary arteriongraphy(CAG). BS, TC,TG,LDL-C,HDL-C,apoA,apoB,Lp(a),uric acid(UA) were analyzed by automatic biochemistry analysisdevice. The change of ST segment electric tension and ejective function(EF) have been detected in All patients. Results:The level of BS was5.63 1.95 mmol/L, 5.56 1.04 mmol/L, 6.13 2.0 mmol/L and 7.83 2.85 mmol/L in control group,SAP group,UAP group and AMI group respectively. The level of BS was higher in AMI groups than that in control group ,SAPgroup and UAP group (p<0.05). The level of BS was positively correlated with TG, change of ST segment electric tension, lesion number of coronary artery and number of atherosclerosis plaques, and it was negatively correlated with HDL-C EF. change of ST segment electric tension, lesion number of coronary artery , number of atherosclerosis plaques, Levels of BS and UA were significantly increasing in patients who suffer from coronary artery disease(CAD) and diabetes mellitus compared with those who had no DM ,and EF was lower in the prior.DM was positively correlated with hypertention and C- type lesion and was negatively correlated with A-type lesion.The level of blood sugar and diabetes mellitus were both positively correlated with angina pectoris attacks and long-term heart events. Multivariate Cox regression analysis revealed that diabetes mellitus was an independent predictor for long-term heart events in patients with ACS. Conclusion: The level of blood sugar and 2-type diabetes mellitus have close relationship with lipid metabolism, myocardial ischemia, characteristic of coronary artery lesion, short-time ACS activity .and can be use as useful predictors assessing ACS risk classification . 2-type diabetes mellitus is a useful predictor for long-term heart events in patients with ACS.
Keywords/Search Tags:blood sugar, 2-type diabetes mellitus, coronary arteriongraphy, angina pectoris, heart events
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